EWSR1 Monoclonal Antibody (5H7), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA547453-Each-of-1 | In Stock | ₹ 43,654.50 |
PIMA547453 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,654.50
GST (18%): ₹ 7,857.81
Total Price: ₹ 51,512.31
Antigen
EWSR1
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 5mM sodium azide
Gene Accession No.
Q01844, Q61545
Gene Symbols
EWSR1
Immunogen
Full length human EWS expressed in and purified from <i>E. coli</i>.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Canine, Equine, Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG2b
Applications
Immunocytochemistry, Immunohistochemistry, Western Blot
Clone
5H7
Conjugate
Unconjugated
Gene
EWSR1
Gene Alias
AC002059.7; bK984G1.4; Ewing sarcoma breakpoint region 1; Ewing sarcoma breakpoint region 1 protein; Ewing sarcoma homolog; Ewings sarcoma EWS-Fli1 (type 1) oncogene; Ews; EWS oncogene; EWS RNA binding protein 1; EWS RNA-binding protein 1; EWS RNA-binding protein variant 6; EWS-FLI1; Ewsh; EWSR1; RNA-binding protein EWS
Host Species
Mouse
Purification Method
Protein A/G
Regulatory Status
RUO
Gene ID (Entrez)
100034010, 14030, 2130, 289752, 609786
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- This gene encodes a multifunctional protein that is involved in various cellular processes, including gene expression, cell signaling, and RNA processing and transport
- The protein includes an N-terminal transcriptional activation domain and a C-terminal RNA-binding domain
- Chromosomal translocations between this gene and various genes encoding transcription factors result in the production of chimeric proteins that are involved in tumorigenesis
- These chimeric proteins usually consist of the N-terminal transcriptional activation domain of this protein fused to the C-terminal DNA-binding domain of the transcription factor protein
- Mutations in this gene, specifically a ttranslocation, are known to cause Ewing sarcoma as well as neuroectodermal and various other tumors
- Alternative splicing of this gene results in multiple transcript variants
- Related pseudogenes have been identified on chromosomes 1 and 14.