ACVR2B Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA120175-Each-of-1 | In Stock | ₹ 47,036.50 |
PIPA120175 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,036.50
GST (18%): ₹ 8,466.57
Total Price: ₹ 55,503.07
Antigen
ACVR2B
Classification
Polyclonal
Conjugate
Unconjugated
Gene
ACVR2B
Gene Alias
activin A receptor type 2B; activin A receptor type IIB; activin A receptor, type IIB; activin receptor IIB; activin receptor type IIB; Activin receptor type-2B; Activine receptor 2b (transmembrane serine kinase); ActRIIB; ACTR-IIB; ActRIIB type II activin receptor B; ACVR2B; HTX4; MGC116908
Host Species
Goat
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
93
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Concentration
0.1 mg/mL
Formulation
PBS with 0.02% sodium azide
Gene Accession No.
Q13705
Gene Symbols
ACVR2B
Immunogen
Recombinant fragment of human Activin Receptor Type IIB.
Quantity
25 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Neutralization: when used at a 1-3 μg/mL this antibody will block 50% of the binding of 30 ng/mL recombinant human activin A to immobilized recombinant human activin receptor IIB/Fc chimera (100 μL of a 0.5 μg/mL solution coating each well) in an ELISA assay
- ACVR2B is a type II member of the TGF-beta family of receptor ser/thr kinases and is involved in the activin and myostatin signaling pathway
- Activins and inhibins are members of the TGF-beta superfamily due to amino acid homology with respect to the conservation of 7 of the 9 cysteine residues common to all TGF-beta forms
- To date, seven type I and five type II activin receptors have been cloned from mammals, including activin receptor IA, activin receptor IIA, activin receptor IB, and activin receptor IIB
- In addition, two splice variants of activin receptor IIA and five splice variants of activin receptor IIB have been reported.