PIPA120184

c-Met Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA120184-Each-of-1 In Stock ₹ 48,905.50

PIPA120184 - Each of 1

₹ 48,905.50

In Stock

Quantity

1

Base Price: ₹ 48,905.50

GST (18%): ₹ 8,802.99

Total Price: ₹ 57,708.49

Antigen

c-Met

Classification

Polyclonal

Conjugate

Unconjugated

Gene

MET

Gene Alias

AI838057; AUTS9; bHLHe59; CG1705; CG1705-PA; CG1705-PB; cmet; c-met; c-met proto-oncogene; c-Met receptor tyrosine kinase; c-Met/HGF receptor; D249; DFNB97; Dmel\CG1705; Dmel_CG1705; DmMet; EC 2.7.10.1; Hepatocyte growth factor receptor; HGF; HGF receptor; HGF receptor c-Met; HGF/SF receptor; HGFR; HGF-SF receptor; juvenile hormone resistance; met; met proto-oncogene; met proto-oncogene (hepatocyte growth factor receptor); met proto-oncogene tyrosine kinase; MET proto-oncogene, receptor tyrosine kinase; Met/Met1; Met; protein tyrosin kinase; methoprene tolerant; Methoprene-tolerant; Methoprene-tolerant protein; Met-PA; Met-PB; Mett; oncogene MET; Par4; Proto-oncogene c-Met; RCCP2; resistance (1) juvenile H; resistance to juvenile hormone; Rst(1)JH; sc MET; scatter factor receptor; SF receptor; soluble c met; tyrosine-protein kinase Met

Host Species

Goat

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

17295

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

ELISA, Immunohistochemistry, Neutralization, Western Blot

Concentration

0.1 mg/mL

Formulation

PBS with no preservative

Gene Accession No.

P16056

Gene Symbols

MET

Immunogen

Recombinant, mouse hepatocyte growth factor receptor (HGFR).

Quantity

25 μg

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • PA1-20184 detects Hepatocyte Growth Factor Receptor in mouse samples and has been successfully used in ELISA, IHC, Neutralizing, and Western blot procedures
  • MET (cMET) is a receptor-like tyrosine kinase whose dysregulation has been linked to many types of human malignancies
  • After activation of the ligand, MET interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, and STAT3
  • There interactions lead to the activation of signaling cascades including RAS-ERK, PI3, kinase-AKT, and PLCgamma-PKC
  • MET plays a role in embryonic development including gastrulation, development of muscles and neurons, angiogenesis, and kidney formation
  • It also plays a role in adults including wound healing, organ regeneration, and tissue remodeling
  • MET has been linked to cancers including gastric, renal, and breast; therefore, making it a target for cancer therapeutics and diagnostic testing.