PIPA120409
GPR26 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA120409-Each-of-1 | In Stock | ₹ 49,083.50 |
PIPA120409 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 49,083.50
GST (18%): ₹ 8,835.03
Total Price: ₹ 57,918.53
Antigen
GPR26
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Gpr26
Gene Alias
9630036A11Rik; A730021D22; DKFZp761H2121; FLJ33774; G protein-coupled receptor 26; Gpr26; G-protein coupled receptor 26; MGC138216; probable G-protein coupled receptor 26
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
2849
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry (Paraffin)
Concentration
1 mg/mL
Formulation
PBS with 0.1% sodium azide
Gene Accession No.
Q8NDV2
Gene Symbols
Gpr26
Immunogen
Synthetic peptide corresponding to the 3rd cytoplasmic loop of human G Protein-Coupled Receptor GPR26.
Quantity
25 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- PA1-20409 detects G Protein-Coupled Receptor GPR26 in human samples
- The G-protein-coupled receptor (GPCR) superfamily is comprised of an estimated 600-1,000 members and is the largest known class of molecular targets with proven therapeutic value
- GPR26 is a brain-specific orphan GPCR with a significant level of constitutive activity
- Its effect is mediated by G(s)-alpha protein that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP
- In the CNS, the highest GPR26 expression is in the amygdala, hippocampus and thalamus
- Weak expression is detected in testis
- GPR26 is down-regulated in glioblastoma
- Depletion of GPR26 has been shown to increase fat storage in C
- elegans, whereas GPR26 deficiency in the hypothalamus is associated with high genetic susceptibility to the onset of obesity in mice
- GPR26 deficiency also causes metabolic complications commonly associated with obesity, including glucose intolerance, hyperinsulinemia, and dyslipidemia.