PIPA120639
TNIK Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA120639-Each-of-1 | In Stock | ₹ 51,798.00 |
PIPA120639 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 51,798.00
GST (18%): ₹ 9,323.64
Total Price: ₹ 61,121.64
Antigen
TNIK
Classification
Polyclonal
Conjugate
Unconjugated
Gene
TNIK
Gene Alias
1500031A17Rik; 4831440I19Rik; AI451411; C530008O15Rik; C630040K21Rik; KIAA0551; RGD1561817; Tnik; TRAF2 and NCK interacting kinase; TRAF2 and NCK-interacting protein kinase
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
23043, 665113
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.01% sodium azide
Gene Accession No.
P83510, Q9UKE5
Gene Symbols
TNIK
Immunogen
Synthetic peptide with a proprietary sequence
Quantity
25 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Suggested positive controls for this product are heart, skeletal muscle and brain
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- TNIK or TRAF2 and NCK interacting kinase is characterized by an N-terminal kinase domain and a C-terminal GCK domain that serves a regulatory function
- TNIK is mainly expression in brain, heart, and spleen and it is a specific effector of RAP2 which regulate actin cytoskeleton
- TNIK is autophosphorylated in a manner dependent upon lys54 in the ATP-binding pocket of its kinase domain and plays a main role in cytoskeleton regulation
- TNIK has also been shown to phosphorylate gelsolin, the principal intracellular and extracellular actin-severing protein, in vitro
- This and evidence from mutational studies suggest that TNIK functions in the regulation of the cytoskeleton.