PIPA124538

TLX Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA124538-Each-of-1 In Stock ₹ 48,905.50

PIPA124538 - Each of 1

₹ 48,905.50

In Stock

Quantity

1

Base Price: ₹ 48,905.50

GST (18%): ₹ 8,802.99

Total Price: ₹ 57,708.49

Antigen

TLX

Classification

Polyclonal

Conjugate

Unconjugated

Gene

NR2E1

Gene Alias

fc30e03; fc39f12; fierce; frc; HTll; Mtl1; Mtll; NR2D1; nr2e1; Nuclear receptor subfamily 2 group E member 1; nuclear receptor subfamily 2, group E, member 1; nuclear receptor TLX; Protein tailless homolog; tailes-related receptor; tailless; tailless homolog; TLL; Tlx; wu:fc30e03; wu:fc39f12; XTLL; zgc:100991

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

7101

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry (Paraffin)

Concentration

1 mg/mL

Formulation

PBS with 0.1% sodium azide

Gene Accession No.

Q9Y466

Gene Symbols

NR2E1

Immunogen

Synthetic peptide, KLH conjugated, corresponding to the N-terminal extracellular domain of human TLX.

Quantity

25 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Description PA1-24538 detects TLX in human samples
  • Nuclear receptor TLX, a NR2 hepatocyte NF4-like receptor, has been shown to affect anterior brain differentiation, retinal development, and vision
  • It has been suggested that TLX targets genes for RAR beta2 and Pax2 during retinal development
  • Homozygous TLX mutant mice are viable at birth but exhibit reduced forebrain development and are more aggressive than wild-type mice
  • Mice with deleted TLX locus exhibit cerebral hypoplasia, blindness, and extreme aggression (fierce (frc) phenotype)
  • TLX expression has been documented in mouse brain and eye
  • ESTs have been isolated from normal human brain libraries.