PIPA124931

Cofilin Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA124931-Each-of-1 In Stock ₹ 51,397.50

PIPA124931 - Each of 1

₹ 51,397.50

In Stock

Quantity

1

Base Price: ₹ 51,397.50

GST (18%): ₹ 9,251.55

Total Price: ₹ 60,649.05

Antigen

Cofilin

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CFL1

Gene Alias

18 kDa phosphoprotein; AA959946; CFL; Cfl1; CFL-1; Cof; COF1; cofilin; cofilin 1; cofilin 1 (non-muscle); cofilin 1, non-muscle; cofilin, non-muscle isoform; Cofilin1; Cofilin-1; cofilin-1-like protein; epididymis secretory protein Li 15; HEL-S-15; n-cofilin; p18

Host Species

Rabbit

Purification Method

IgG fraction

Regulatory Status

RUO

Gene ID (Entrez)

1072, 12631, 29271, 476022

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration

11.4 mg/mL

Formulation

0.01M PBS with 15mM sodium azide; pH 7.4

Gene Accession No.

P18760, P23528, P45592

Gene Symbols

CFL1

Immunogen

Synthetic peptide, conjugated to maleimide-activated KLH, corresponding to residues 154-166 of human cofilin with an N-terminal added cysteine.

Quantity

50 μL

Primary or Secondary

Primary

Target Species

Canine, Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Recommended positive controls: A431, PC-12, NIH3T3, MDCK
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • Cofilin binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity
  • Regulates actin cytoskeleton dynamics
  • Important for normal progress through mitosis and normal cytokinesis
  • Plays a role in the regulation of cell morphology and cytoskeletal organization
  • Required for the up-regulation of atypical chemokine receptor ACKR2 from endosomal compartment to cell membrane, increasing its efficiency in chemokine uptake and degradation
  • Required for neural tube morphogenesis and neural crest cell migration.