PIPA129513

Neuropilin 1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA129513-Each-of-1 In Stock ₹ 52,421.00

PIPA129513 - Each of 1

₹ 52,421.00

In Stock

Quantity

1

Base Price: ₹ 52,421.00

GST (18%): ₹ 9,435.78

Total Price: ₹ 61,856.78

Antigen

Neuropilin 1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

NRP1

Gene Alias

A5 protein; BDCA4; C530029I03; CD304; Neuropilin; neuropilin 1; Neuropilin1; neuropilin-1; Neuropilin-1 precursor (A5 protein); NP1; NP-1; Npn1; NPN-1; NRP; NRP 1; Nrp1; sNRP 1; sNRP1; soluble NRP 1; soluble NRP1; transmembrane receptor; vascular endothelial cell growth factor 165 receptor; VEGF165R

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

18186, 246331, 8829

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)

Concentration

0.5 mg/mL

Formulation

PBS with 0.05% BSA and 0.05% sodium azide

Gene Accession No.

O14786, P97333, Q9QWJ9

Gene Symbols

NRP1

Immunogen

Synthetic peptide TDLDKKNTEIKIDET, corresponding to C terminal amino acids 813 - 827 of Rat Neuropilin 1.

Quantity

50 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • This antibody recognizes a 130 kDa protein from mouse and rat brain tissue extract in western blot
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • Neuropilin 1 is a 923 amino acid containing membrane bound coreceptor to a tyrosine kinase receptor belonging to the neuropilin family with two CUB domains, two F5/8 type C domains and a MAM domain
  • Neuropilin 1 forms a heterodimer with NRP2 (Neuropilin 2) and is known to bind to plexin (PLXNB1) to form semaphorin receptors
  • Expressed mostly in the nervous system this receptor is implicated in a wide range of functions including in the development of the cardiovascular system, angiogenesis, repulsive axon guidance, formation of certain neuronal circuits, cell survival, control of neuronal migration and organogenesis outside the nervous system
  • This semaphorin receptor functions as receptors for both the semaphorins and vascular endothelial growth factor and is also a regulator of VEGF-induced angiogenesis
  • Neuropilin 1 may be involved in aggressive advanced prostate carcinoma and in the progression of breast cancer.