PIPA125472

SIRT2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA125472-Each-of-1 In Stock ₹ 46,591.50

PIPA125472 - Each of 1

₹ 46,591.50

In Stock

Quantity

1

Base Price: ₹ 46,591.50

GST (18%): ₹ 8,386.47

Total Price: ₹ 54,977.97

Antigen

SIRT2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SIRT2

Gene Alias

5730427M03Rik; 5E5 antigen; mSIR2L2; NAD-dependent deacetylase sirtuin-2; NAD-dependent protein deacetylase sirtuin-2; Regulatory protein SIR2 homolog 2; silent information regulator 2; silent mating type information regulation 2, (S.cerevisiae, homolog)-like; sirtuin 2; SIR2; SIR2L; SIR2L2; SIR2-like protein 2; sir2-related protein type 2; Sirt2; sirtuin 2; sirtuin type 2; sirtuin-2

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

22933, 64383

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1.33 mg/mL

Formulation

0.01M PBS with 1% BSA and 15mM sodium azide; pH 7.4

Gene Accession No.

Q8IXJ6, Q8VDQ8

Gene Symbols

SIRT2

Immunogen

Synthetic peptide corresponding to the C-terminal residues 722-737 of mouse SIR2/SIRT2, with a C-terminal added lysine.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Recommended positive controls: NIH3T3
  • Predicted molucular weight of 43 kDa
  • The SIRT2 protein (also known as Sirtuin for Silent Mating Type Information 2-Homolog) is a NAD-dependent deacytylase (NDAC) that has been shown to control gene silencing, cell cycle, and DNA damage repair
  • It is believed that SIRT2 may act as a tumor suppressor in human gliomas and may also serve as a novel molecular marker for these cells
  • SIRT2 has also been shown to act as a redox sensor to help regulate muscle gene expression in response to food intake and exercise
  • SIRT2 acts in the phosphorylation cascade involving mitosis where SIRT2 is phosphorylated in late G2 phase, during M phase, and into cytokinesis.