PIPA129424

mGluR3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA129424-Each-of-1 In Stock ₹ 48,905.50

PIPA129424 - Each of 1

₹ 48,905.50

In Stock

Quantity

1

Base Price: ₹ 48,905.50

GST (18%): ₹ 8,802.99

Total Price: ₹ 57,708.49

Antigen

mGluR3

Classification

Polyclonal

Formulation

tris glycine with 1% BSA and 0.1% sodium azide; pH 7.8

Gene Accession No.

P31422, Q14832, Q9QYS2

Gene Symbols

GRM3

Immunogen

synthetic peptide TKVDEAEYM, corresponding to amino acids 118-126 of Rat metabotropic Glutamate Receptor 3.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Applications

Western Blot

Conjugate

Unconjugated

Gene

GRM3

Gene Alias

0710001G23Rik; G protein-coupled receptor, family C, group 1, member C; GLUR3; glutamate metabotropic receptor 3; glutamate receptor; glutamate receptor, metabotropic 3; Gprc1c; GRM3; M mGlu3; Metabotropic glutamate receptor 3; mGlu3; mGluR3

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

108069, 24416, 2913

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Recommended positive controls: Rat Cerebellar and cortical Membrane
  • Glutamate is the main excitatory neurotransmitter in the brain
  • For many years it had been considered to act only on the ligand-gated receptor channels-termed NMDA, AMPA and kainite receptors that are involved in the fast excitatory synaptic transmission
  • Recently, glutamate has been shown to regulate enzymes producing second messengers via specific receptors coupled to G-proteins
  • These receptors are called metabotropic glutamate receptors
  • In expression systems, Group-I receptors stimulate phospholipase C as revealed by an increase in phosphoinositide turnover and calcium release from internal stores
  • Group-II and -III receptors are coupled to the inhibition of adenylyl cyclase
  • The Group-I receptors include mGluR1a and mGluR5
  • The Group-II receptors in include mGluR2 and mGluR3.