PIPA132828

mGluR7 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA132828-Each-of-1 In Stock ₹ 48,905.50

PIPA132828 - Each of 1

₹ 48,905.50

In Stock

Quantity

1

Base Price: ₹ 48,905.50

GST (18%): ₹ 8,802.99

Total Price: ₹ 57,708.49

Antigen

mGluR7

Classification

Polyclonal

Conjugate

Unconjugated

Gene

GRM7

Gene Alias

6330570A01Rik; BB176677; C030018L03; E130018M02Rik; FLJ40498; G protein-coupled receptor GRM7; G protein-coupled receptor, family C, group 1, member G; GLUR7; glutamate metabotropic receptor 7; glutamate receptor; glutamate receptor, metabotropic 7; Gpr1g; Gprc1g; GRM7; Metabotropic glutamate receptor 7; metabotropic glutamate receptor mGluR7; metabotropic glutamate receptor subtype 7b; MGLU7; mGlu7a receptor; MGLUR7; PPP1R87; protein phosphatase 1, regulatory subunit 87

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

2917

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.1% sodium azide

Gene Accession No.

Q14831

Gene Symbols

GRM7

Immunogen

Synthetic 19 amino acid peptide from N-terminal extracellular domain of human mGluR7

Quantity

25 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Description PA1-32828 detects GPRC1G from human samples
  • L-glutamate is the major excitatory neurotransmitter in the central nervous system, and it activates both ionotropic and metabotropic glutamate receptors
  • Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions
  • The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into three groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties
  • Group I includes GRM1 and GRM5, and these receptors have been shown to activate phospholipase C
  • Group II includes GRM2 and GRM3, while Group III includes GRM4, GRM6, GRM7 and GRM8
  • Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities
  • Multiple transcript variants encoding different isoforms have been found for this gene.