PIPA131218

WWOX Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA131218-Each-of-1 In Stock ₹ 48,905.50

PIPA131218 - Each of 1

₹ 48,905.50

In Stock

Quantity

1

Base Price: ₹ 48,905.50

GST (18%): ₹ 8,802.99

Total Price: ₹ 57,708.49

Antigen

WWOX

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Wwox

Gene Alias

5330426P09Rik; 9030416C10Rik; D16S432E; EIEE28; FOR; FRA16D; Fragile site FRA16D oxidoreductase; HHCMA56; PRO0128; SCAR12; SDR41C1; Short chain dehydrogenase/reductase family 41C member 1; short chain dehydrogenase/reductase family 41C, member 1; WOX1; WW domain containing oxidoreductase; WW domain-containing oxidoreductase; WW domain-containing protein WWOX; WW-domain oxidoreductase; Wwox

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

292041, 51741, 80707

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Dot Blot, ELISA

Concentration

0.5 mg/mL

Formulation

tris glycine with 0.5% BSA, 30% glycerol and 0.02% Sodium azide; pH 7.4-7.9

Gene Accession No.

Q91WL8, Q9NZC7

Gene Symbols

Wwox

Immunogen

Synthetic peptide.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • PA1-31218 detects WWOX2 from human, rat, mouse samples
  • WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing
  • This gene encodes a protein which contains 2 WW domains and a short-chain dehydrogenase/reductase domain (SRD)
  • The highest normal expression of this gene is detected in hormonally regulated tissues such as testis, ovary, and prostate
  • This expression pattern and the presence of an SRD domain suggest a role for this gene in steroid metabolism
  • The encoded protein is more than 90% identical to the mouse protein, which is an essential mediator of tumor necrosis factor-alpha-induced apoptosis, suggesting a similar, important role in apoptosis for the human protein
  • In addition, there is evidence that this gene behaves as a suppressor of tumor growth
  • Alternative splicing of this gene generates transcript variants that encode different isoforms.