PIPA5100128

BBS10 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5100128-Each-of-1 In Stock ₹ 46,502.50

PIPA5100128 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

BBS10

Classification

Polyclonal

Conjugate

Unconjugated

Gene

BBS10

Gene Alias

1300007O09Rik; AI452285; Bardet-Biedl syndrome 10; Bardet-Biedl syndrome 10 (human); Bardet-Biedl syndrome 10 protein; Bardet-Biedl syndrome 10 protein homolog; Bbs10; C12orf58; RGD1560748; si:dkey-30c15.16

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

100034535, 71769, 79738

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q8TAM1, Q9DBI2

Gene Symbols

BBS10

Immunogen

A synthesized peptide derived from human BBS10(Accession Q8TAM1), corresponding to amino acid residues A160-V210.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Zebrafish

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total BBS10
  • BBS10 is a member of the Bardet-Biedl syndrome (BBS) gene family
  • Bardet-Biedl syndrome is an autosomal recessive disorder characterized by progressive retinal degeneration, obesity, polydactyly, renal malformation and mental retardation
  • The proteins encoded by BBS gene family members are structurally diverse and the similar phenotypes exhibited by mutations in BBS gene family members is likely due to their shared roles in cilia formation and function
  • Many BBS proteins localize to the basal bodies, ciliary axonemes, and pericentriolar regions of cells
  • BBS proteins may also be involved in intracellular trafficking via microtubule-related transport
  • The protein encoded by this gene is likely not a ciliary protein but rather has distant sequence homology to type II chaperonins
  • As a molecular chaperone, this protein may affect the folding or stability of other ciliary or basal body proteins
  • Inhibition of this protein's expression impairs ciliogenesis in preadipocytes.