BBS9 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5100220-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5100220 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
BBS9
Classification
Polyclonal
Conjugate
Unconjugated
Gene
BBS9
Gene Alias
B1; Bardet-Biedl syndrome 9; Bardet-Biedl syndrome 9 (human); bardet-Biedl syndrome 9 protein; Bardet-Biedl syndrome 9 protein homolog; BBS9; C18; D1; E130103I17Rik; EST 3159894; parathyroid hormone-responsive B1 gene protein; Parathyroid hormone-responsive B1 gene protein homolog; protein PTHB1; PTHB1; PTH-responsive osteosarcoma B1 protein; RGD1308472
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
27241, 319845
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
Q3SYG4, Q811G0
Gene Symbols
BBS9
Immunogen
A synthesized peptide derived from human BBS9(Accession Q3SYG4), corresponding to amino acid residues G767-D817.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of total BBS9
- The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia
- The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function
- This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome
- Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane
- Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane
- Required for proper BBSome complex assembly and its ciliary localization.