PIPA5101420
Amphiphysin Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5101420-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5101420 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
Amphiphysin
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Amph
Gene Alias
Amph; AMPH1; amphiphysin; amphiphysin (Stiff-Mann syndrome with breast cancer 128kD autoantigen); amphiphysin 1; amphiphysin I; HGNC:471
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
218038, 273, 60668
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
O08838, P49418, Q7TQF7
Gene Symbols
Amph
Immunogen
A synthesized peptide derived from human AMPH(Accession P49418), corresponding to amino acid residues S139-E189.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of total AMPH
- Amphiphysins, members of the BAR (Bin-Amphiphysin-Rvsp) protein super family, play a key role in clathrin-mediated endocytosis of synaptic vesicles (SVs)
- All members of the BAR family share a highly conserved N-terminal BAR domain and a C-terminal Src homology (SH3) domain
- Two isoforms of amphiphysin have been identified and act in concert as a heterodimer
- Amphiphysins interact via its carboxy-terminal SH3 domain with dynamin, synaptojanin and clathrin
- These complexes are implicated in synaptic vesicle recycling at nerve terminal
- Amphiphysins were also identified as the dominant autoantigen in paraneoplastic Stiff-Man Syndrome.