PIPA5101434
Aquaporin 12 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5101434-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5101434 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
Aquaporin 12
Classification
Polyclonal
Conjugate
Unconjugated
Gene
AQP12B
Gene Alias
AQP12; AQP-12; AQP12A; AQP12B; AQP-12B; AQPX2; aquaporin 12; aquaporin 12A; aquaporin 12B; aquaporin X2; aquaporin-12; aquaporin-12A; Aquaporin-12B; INSSA3; insulin synthesis associated 3; RGD1562727
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
375318, 653437
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
A6NM10, Q8IXF9
Gene Symbols
AQP12A, AQP12B
Immunogen
A synthesized peptide derived from human AQP12A(Accession Q8IXF9), corresponding to amino acid residues V232-R282.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of total AQP12
- Aquaporin 12 (AQP12) is the most recently identified member of the mammalian AQP family and is specifically expressed in pancreatic acinar cells
- In vitro expression studies have revealed that AQP12 is localized at intracellular sites
- To determine the physiological roles of AQP12 in the pancreas, we generated knockout mice for this gene (AQP12-KO)
- No obvious differences were observed under normal conditions between wild-type (WT) and AQP12-KO mice in terms of growth, blood chemistry, pancreatic fluid content, or histology
- However, when we induced pancreatitis through the administration of a cholecystokinin-8 (CCK-8) analog, the AQP12-KO mice showed more severe pathological damage to this organ than WT mice.