PIPA5101704

NPDC1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5101704-Each-of-1 In Stock ₹ 46,502.50

PIPA5101704 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

NPDC1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

NPDC1

Gene Alias

AI314472; CAB; CAB-; CAB1; CAB-1; DKFZP586J0523; Neural proliferation differentiation and control protein 1; neural proliferation differentiation control-1 protein; neural proliferation, differentiation and control 1; neural proliferation, differentiation and control gene 1; neural proliferation, differentiation and control, 1; NPDC1; NPDC-1; RP23-47P18.6

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

18146, 296562, 56654

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q64322, Q9NQX5

Gene Symbols

NPDC1

Immunogen

A synthesized peptide derived from human NPDC1(Accession Q9NQX5), corresponding to amino acid residues I188-G238.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total NPDC1
  • The discovery of NPDC-1 (neuronal proliferation, differentiation and control protein 1) was the result of a study of genes that were preferentially expressed in immortalized neural precursor cell lines at the onset of contact inhibition of proliferation and subsequent differentiation
  • It was further found that transfection of transformed cells with NPDC-1 led to increased doubling times and suppression of many characteristics of transformation
  • NPDC-1 is differentially expressed in brain and lung and has been shown to interact directly with the transcription factor E2F-1 as well as D-type cyclins and cdk2
  • NPDC-1 has been identified as a modulator of transcriptiona levents mediated by retinoic acid and the protein level and activity of NPDC-1 have been shown to be regulated by phosphorylation mediated proteasomal degradation.