PIPA5102425

IL-6R Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5102425-Each-of-1 In Stock ₹ 54,023.00

PIPA5102425 - Each of 1

₹ 54,023.00

In Stock

Quantity

1

Base Price: ₹ 54,023.00

GST (18%): ₹ 9,724.14

Total Price: ₹ 63,747.14

Antigen

IL-6R

Classification

Polyclonal

Conjugate

Unconjugated

Gene

IL6R

Gene Alias

CD126; CD126 antigen; gp80; IL-6 Receptor; il-6 receptor alpha; IL-6 receptor alpha chain; IL-6 receptor subunit alpha; IL6Q; IL6R; IL-6R; IL-6R 1; IL-6R subunit alpha; IL6R1; IL-6R-1; Il6ra; IL-6RA; IL-6R-alpha; IL6RQ; ILN; Interleukin; interleukin 6 receptor; interleukin 6 receptor, alpha; interleukin-6 receptor subunit alpha; Membrane glycoprotein 80; MGC104991

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

16194, 3570

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P08887, P22272

Gene Symbols

IL6R, Il6ra

Immunogen

A synthesized peptide derived from human IL6R(Accession P08887), corresponding to amino acid residues L45-S95.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total IL6R
  • Interleukin 6 receptor (IL6R), also known as CD126 (Cluster of Differentiation 126), is a type I cytokine receptor
  • This gene encodes a subunit of the interleukin 6 (IL6) receptor complex
  • Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response
  • The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines
  • Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer
  • Alternatively spliced transcript variants encoding distinct isoforms have been reported
  • A pseudogene of this gene is found on chromosome 9.