PIPA5102501
Amphiregulin Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5102501-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5102501 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
Amphiregulin
Classification
Polyclonal
Conjugate
Unconjugated
Gene
AREG
Gene Alias
amphiregulin; amphiregulin B; AR; AREG; AREGB; colorectum cell-derived growth factor; CRDGF; Mcub; MGC13647; schwannoma-derived growth factor; SDGF
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
11839, 29183, 374
Content And Storage
-20°C
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
P15514, P24338, P31955
Gene Symbols
AREG
Immunogen
A synthesized peptide derived from human AREG(Accession P15514), corresponding to amino acid residues G60-P110.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of total AREG
- Amphiregulin (AR) binds to EGF-Receptor (EGFR) with lower affinity than EGF
- The mature secreted form AR is an 84-amino acid residue glycosylated polypeptide growth regulator, which is generated by proteolytic processing of a 252-amino acid transmembrane precursor
- Seven different polypeptide ligands, which derive from distinct genes, are capable of binding to the extracellular domain of EGFR
- These ligands include EGF, TGFalpha, AR, HB-EGF, cripto-1, epiregulin, and betacellulin
- All of these growth factors contain a characteristic EGF-like domain which is defined by 6 evenly spaced cysteine residues that generate 3 loops through the formation of disulfide bonds
- AR protein has been localized by immunohistochemistry to the epithelium of the colon, stomach, pancreas, breast, and placenta
- AR is reportedly overexpressed in human cancers of breast, colon, stomach, and pancreas.