Phospho-IRAK4 (Thr345, Ser346) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5102849-Each-of-1 | In Stock | ₹ 45,078.50 |
PIPA5102849 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,078.50
GST (18%): ₹ 8,114.13
Total Price: ₹ 53,192.63
Antigen
Phospho-IRAK4 (Thr345, Ser346)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
IRAK4
Gene Alias
8430405M07Rik; 9330209D03Rik; interleukin 1 receptor associated kinase 4; interleukin-1; interleukin-1 receptor-associated kinase 4; IPD1; Irak4; IRAK-4; NY-REN-64; REN64; renal carcinoma antigen NY-REN-64
Host Species
Rabbit
Purification Method
sequential chromatography
Regulatory Status
RUO
Gene ID (Entrez)
266632, 300177, 51135
Content And Storage
-20°C
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
Q8R4K2, Q9NWZ3
Gene Symbols
IRAK4
Immunogen
A synthesized peptide derived from human IRAK4(Accession Q9NWZ3), corresponding to amino acid residues around phosphorylated Ser346.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of IRAK4 only when phosphorylated at Thr345/Ser346
- IL-1 receptor associated kinases (IRAKs) are serine/threonine kinases involved in signaling via Toll/IL-1 pathways
- Overexpression of IRAK-4 activates NF-kappa-B and MAPK pathways
- IRAK-4 interacts with and phosphorylates IRAK-1
- IRAK-4-deficient animals are completely resistant to the challenge with LPS
- Animals and humans lacking IRAK-4 are impaired in their responses to viral and bacterial challenges
- Members in IRAK/Pelle family play a central role in IL-1R/TLR mediated inflammatory responses and in innate immunity.