GUCY1B2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5103135-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5103135 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
GUCY1B2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
GUCY1B2
Gene Alias
B930025B03; GCS beta2; GC-SB2; GCS-beta2; GCS-beta-2; guanylate cyclase 1 soluble subunit beta 2 (pseudogene); guanylate cyclase 1, soluble, beta 2; Guanylate cyclase soluble beta 2 (GTP pyrophosphate - lyase); guanylate cyclase soluble subunit beta-2; Guanylate cyclase, soluble, beta 2 (GTP pyrophosphate - lyase); Gucy1b2; Gucy1b2a; Gucy1b2b; SGC; soluble guanylate cyclase beta 2a; soluble guanylate cyclase beta 2b; soluble guanylyl cyclase beta2 subunit
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
239134, 25206, 2974
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
O75343, P22717
Gene Symbols
GUCY1B2
Immunogen
A synthesized peptide derived from human GUCY1B2(Accession O75343), corresponding to amino acid residues P581-L617.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of total GCS beta 2
- Guanylate cyclases belong to the adenylyl cyclase class-4/guanylyl cyclase family
- There are two forms of guanylate cyclase
- The soluble form, known as GCS or sGC, act as receptors for nitric oxide
- The membrane-bound receptor form, known as GC, are peptide hormone receptors
- GCS is a cGMP-synthesizing enzyme, which is the major receptor for the neurotransmitter nitric oxide (NO)
- It plays a crucial role in smooth muscle contractility, platelet reactivity and neurotransmission
- GCS is a heme containing heterodimer, consisting of one 72 kDa alpha subunit and one 65 kDa beta subunit
- The heme moeity mediates NO activation, and this heme group also binds carbon monoxide, which weakly stimulates the enzyme.