NEIL2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5103829-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5103829 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
NEIL2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
NEIL2
Gene Alias
DNA glycosylase/AP lyase Neil2; DNA-(apurinic or apyrimidinic site) lyase Neil2; Endonuclease 8-like 2; endonuclease VIII-like 2; Gm1212; NEH2; nei endonuclease VIII-like 2; nei endonuclease VIII-like 2 (E. coli); nei homolog 2; nei like 2; nei like 2 (E. coli); nei like DNA glycosylase 2; NEI2; Neil2; nei-like DNA glycosylase 2; nei-like protein 2
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
252969, 382913
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
Q6R2P8, Q969S2
Gene Symbols
NEIL2
Immunogen
A synthesized peptide derived from human NEIL2(Accession Q969S2), corresponding to amino acid residues G128-Y178.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of total NEIL2
- Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents
- Has DNA glycosylase activity towards 5-hydroxyuracil and other oxidized derivatives of cytosine with a preference for mismatched double-stranded DNA (DNA bubbles)
- Has low or no DNA glycosylase activity towards thymine glycol, 2-hydroxyadenine, hypoxanthine and 8-oxoguanine
- Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand
- Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.