HLA-DQB2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5103888-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5103888 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
HLA-DQB2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
HLA-DQB2
Gene Alias
DV19.1 (major histocompatibility complex, class II, DQ beta 2 (HLA-DXB)); HLA class II histocompatibility antigen, DQ beta 2 chain; HLA class II histocompatibility antigen, DX beta chain; HLA-DQB1; HLA-DQB2; HLA-DXB; major histocompatibility complex, class II, DQ beta 1; major histocompatibility complex, class II, DQ beta 2; MHC class II antigen DQB2
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
3120
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
P05538
Gene Symbols
HLA-DQB2
Immunogen
A synthesized peptide derived from human HLA-DQB2(Accession P05538), corresponding to amino acid residues G233-H268.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of total HLA-DQB2
- HLA-DQB2 belongs to the family of HLA class II beta chain paralogs
- Class II molecules are heterodimers consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane
- They play a central role in the immune system by presenting peptides derived from extracellular proteins
- Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages)
- Polymorphisms in the alpha and beta chains specify the peptide binding specificity, and typing for these polymorphisms is routinely done for bone marrow transplantation
- However this gene, HLA-DQB2, is not routinely typed, as it is not thought to have an effect on transplantation
- There is conflicting evidence in the literature and public sequence databases for the protein-coding capacity of HLA-DQB2
- HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.