Phospho-CDK6 (Tyr292) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5104684-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5104684 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
Phospho-CDK6 (Tyr292)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
CDK6
Gene Alias
5830411I20; AI504062; CDK6; CDKN6; Cell division protein kinase 6; CR2 protein kinase; Crk2; cyclin dependent kinase 6; cyclin-dependent kinase 6; MCPH12; MGC59692; PLSTIRE; Serine/threonine-protein kinase PLSTIRE
Host Species
Rabbit
Purification Method
sequential chromatography
Regulatory Status
RUO
Gene ID (Entrez)
1021, 12571
Content And Storage
-20°C
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
Q00534, Q64261
Gene Symbols
CDK6
Immunogen
A synthesized peptide derived from human CDK6(Accession Q00534), corresponding to amino acid residues around phosphorylated Tyr292.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of CDK6 only when phosphorylated at Tyr292
- CDK6 functions as a cell-cycle initiator protein
- This protein is coexpressed and copurified with CyclinD1
- They are critical regulators of cell cycle progression
- The prototype member of this family, p34cdc2, and a related protein cdk2, function late in the cycle while cdk4 and cdk6 are critically involved in G1 to S progression
- CDK6 is essential for cell proliferation within the dentate gyrus of the hippocampus and the cuventricular zone of the lateral ventricles
- Mutations in the gene results in microcephaly 12, primary, autosomal recessive (MCPH12).