PIPA5104890

Phospho-HNF4A (Ser313) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5104890-Each-of-1 In Stock ₹ 46,502.50

PIPA5104890 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

Phospho-HNF4A (Ser313)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

HNF4A

Gene Alias

alpha transcription factor 4; FLJ39654; FRTS4; hepatic nuclear factor 4 alpha; hepatic nuclear factor 4, alpha; hepatocyte nuclear factor 4 alpha; hepatocyte nuclear factor 4, alpha; hepatocyte nuclear factor 4-alpha; HNF4; Hnf-4; HNF4 alpha; Hnf4a; HNF4a7; HNF4a8; HNF4a9; Hnf4alpha; HNF-4-alpha; HNF4-alpha; HNF4alpha10; HNF4alpha10/11/12; HNF4alpha11; HNF4alpha12; MODY; MODY1; NR2A1; NR2A21; Nuclear receptor 2A1; nuclear receptor subfamily 2 group A member 1; TCF; TCF14; TCF-14; Transcription factor 14; transcription factor HNF-4

Host Species

Rabbit

Purification Method

sequential chromatography

Regulatory Status

RUO

Gene ID (Entrez)

15378, 25735, 3172

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P22449, P41235, P49698

Gene Symbols

HNF4A

Immunogen

A synthesized peptide derived from human HNF4A(Accession P41235), corresponding to amino acid residues around phosphorylated Ser313.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of HNF4 alpha only when phosphorylated at Serine 313
  • Hepatocyte nuclear factor 4 alpha (HNF4 alpha) is an orphan nuclear receptor
  • HNF4a is expressed in the liver, kidney, intestine, and pancreas
  • Mutation of HNF4a in humans has been associated with maturity-onset diabetes of the young type 1 (MODY1)
  • HNF4 binds to DNA as an exclusive homodimer
  • The HNF4a gene is alternatively spliced and may generate up to nine different isoforms, HNF4a1 through HNF4a9.