Phospho-IRF4 (Tyr122, Tyr125) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5105214-Each-of-1 | In Stock | ₹ 45,078.50 |
PIPA5105214 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,078.50
GST (18%): ₹ 8,114.13
Total Price: ₹ 53,192.63
Antigen
Phospho-IRF4 (Tyr122, Tyr125)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
IRF4
Gene Alias
AI385587; interferon regulatory factor 4; Irf4; IRF-4; LSIRF; Lymphocyte-specific interferon regulatory factor; multiple myeloma oncogene 1; MUM1; NF-EM5; PU.1 interaction partner; Sfpi1/PU.1 interaction partner; SHEP8; Spip; Transcriptional activator PIP
Host Species
Rabbit
Purification Method
sequential chromatography
Regulatory Status
RUO
Gene ID (Entrez)
16364, 291100, 3662
Content And Storage
-20°C
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
Q15306, Q64287
Gene Symbols
IRF4
Immunogen
A synthesized peptide derived from human IRF4(Accession Q15306), corresponding to amino acid residues around phosphorylated Tyr122.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of IRF4 only when phosphorylated at Y122/125
- The IRF (interferon regulatory factor) family of transcription factors are characterized by an unique tryptophan pentad repeat DNA-binding domain
- The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes
- IRF4 is lymphocyte specific and negatively regulates toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems
- A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma
- Alternatively spliced transcript variants have been found.