Phospho-VASP (Ser157) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5104918-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5104918 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
Phospho-VASP (Ser157)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
VASP
Gene Alias
Enah/Vasp-like; I79_012660; Unknown (protein for MGC:127789); vasodilator stimulated phosphoprotein; vasodilator-stimulated phosphoprotein; vasodilator-stimulated phosphoprotein (VASP); VASP
Host Species
Rabbit
Purification Method
sequential chromatography
Regulatory Status
RUO
Gene ID (Entrez)
22323, 361517, 7408
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
P50552, P70460
Gene Symbols
VASP
Immunogen
A synthesized peptide derived from human VASP(Accession P50552), corresponding to amino acid residues around phosphorylated Ser157.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of VASP only when phosphorylated at Serine 157
- Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family
- Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions
- In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins
- Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin
- VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility
- VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions
- VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG.