PIPA5105419
Phospho-VAMP4 (Ser88) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5105419-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5105419 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
Phospho-VAMP4 (Ser88)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
VAMP4
Gene Alias
D1Ertd147e; vamp; VAMP24; VAMP4; VAMP-4; vesicle associated membrane protein 4; vesicle-associated membrane protein 4
Host Species
Rabbit
Purification Method
sequential chromatography
Regulatory Status
RUO
Gene ID (Entrez)
364033, 53330, 8674
Content And Storage
-20°C
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
O70480, O75379
Gene Symbols
VAMP4
Immunogen
A synthesized peptide derived from human VAMP4(Accession O75379), corresponding to amino acid residues around phosphorylated Ser88.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of VAMP4 only when phosphorylated at Ser88
- The vesicle associated membrane proteins (VAMP) or synaptobrevins are calcium binding proteins specific to eukaryotes
- VAMPs, along with synaptosomal associated protein of 25 kDa (SNAP-25) and syntaxin, form the core complex of soluble NSF attachment protein receptor (SNARE) proteins that interact with the soluble proteins N-ethylmaleimide-sensitive factor (NSF) and alpha-SNAP
- These membrane associated proteins play a key role in the regulation of vesicle membrane fusion with the plasma membrane
- The Clostridium tetani neurotoxin is a metalloprotease with specificity for VAMP
- In Alzheimer’s disease, VAMP levels of all isoforms appear to be significantly lowered.