Phospho-14-3-3 zeta (Ser58) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5104934-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5104934 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
Phospho-14-3-3 zeta (Ser58)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Ywhaz
Gene Alias
1110013I11Rik; 14-3-3 delta; 14-3-3 protein zeta/delta; 14-3-3 protein/cytosolic phospholipase A2; 14-3-3 zeta; 1433Z; 14-3-3z; 14-3-3zeta; 14-3-3-zeta; 143Z; AI596267; AL022924; AU020854; epididymis luminal protein 4; epididymis secretory protein Li 3; epididymis secretory protein Li 93; factor activating exoenzyme S; FAS; HEL4; HEL-S-3; HEL-S-93; KCIP-1; mitochondrial import stimulation factor S1 subunit; Msfs1; phospholipase A2; protein kinase C inhibitor protein 1; protein kinase C inhibitor protein-1; SEZ-2; tyrosine 3/tryptophan 5 -monooxygenase activation protein, zeta polypeptide; tyrosine 3/tryptophan 5-monooxygenase activation protein zeta polypeptide; tyrosine 3-monooxygenase tryptophan 5-monooxygenase activation protein; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, delta polypeptide; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta; tyrosine 3-
Host Species
Rabbit
Purification Method
sequential chromatography
Regulatory Status
RUO
Gene ID (Entrez)
22631, 25578, 7534
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
P63101, P63102, P63104
Gene Symbols
Ywhaz
Immunogen
A synthesized peptide derived from human YWHAZ(Accession P63104), corresponding to amino acid residues around phosphorylated Ser58.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of 14-3-3 zeta only when phosphorylated at Serine 58
- At least seven isoforms comprise the highly conserved 14-3-3 family of homo- and heterodimeric proteins that are abundantly expressed in all eukaryotic cells
- Although more than seven isoforms of 14-3-3 have been described, some redundancies have appeared upon sequencing
- The 14-3-3s are thought to be key regulators of signal transduction events mediated through their binding to serine-phosphorylated proteins
- By interacting with Cdc25C, 14-3-3 regulates entry into the cell cycle and through interaction with Bad, prevents apoptosis
- Other proteins that have been shown to bind to 14-3-3s include members of the protein kinase C family, Cbl, IRS-1, polyoma middle-T antigen, nitrate reductase, S-raf and the IGF-1 receptor
- Detection of 14-3-3 proteins in cerebrospinal fluid has been shown to be useful in the differential diagnosis of Creutzfeldt-Jakob disease and other prion diseases.