Phospho-IRAK-M (Ser510) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5105121-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5105121 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
Phospho-IRAK-M (Ser510)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
IRAK3
Gene Alias
4833428C18Rik; AI563835; ASRT5; FLJ13601; IL-1 receptor-associated kinase M; interleukin 1 receptor associated kinase 3; interleukin-1 receptor-associated kinase 3; IRAK3; IRAK-3; IRAKM; IRAK-M
Host Species
Rabbit
Purification Method
sequential chromatography
Regulatory Status
RUO
Gene ID (Entrez)
11213, 314870, 73914
Content And Storage
-20°C
Form
Liquid
Applications
Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
Q8K4B2, Q9Y616
Gene Symbols
IRAK3
Immunogen
A synthesized peptide derived from human IRAK3(Accession Q9Y616), corresponding to amino acid residues around phosphorylated Ser510.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of IRAK3 only when phosphorylated at Ser510
- IRAK3 serine/threonine kinase or interleukin-1 receptor-associated kinase 3 is a member of the interleukin-1 receptor-associated kinase protein family which are essential components of the Toll/IL-R immune signal transduction pathways
- IRAK3 is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling
- IRAK3 mediates critical aspects of innate immunity that result in an immunocompromised state during sepsis
- Mutations in IRAK3 are associated with a susceptibility to asthma.