GATA3 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5105295-Each-of-1 | In Stock | ₹ 46,858.50 |
PIPA5105295 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,858.50
GST (18%): ₹ 8,434.53
Total Price: ₹ 55,293.03
Antigen
GATA3
Classification
Polyclonal
Conjugate
Unconjugated
Gene
GATA3
Gene Alias
EGK_19445; GATA binding factor-3; GATA binding protein 3; GATA binding protein-3; GATA3; Gata-3; GATA-binding factor 3; GATA-binding protein 3; HDR; HDRS; jal; MGC2346; MGC5199; MGC5445; Trans-acting T-cell-specific transcription factor GATA-3; Transacting T-cell-specific transcription factor GATA-3
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
14462, 2625, 85471
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
P23771, P23772
Gene Symbols
GATA3
Immunogen
A synthesized peptide derived from human GATA3(Accession P23771), corresponding to amino acid residues C284-G334.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of total GATA3
- The genes for all 4 subunits of the T-cell antigen receptor (alpha, beta, gamma and delta) are controlled by distinct enhancers and their enhancer-binding proteins
- Marine and Winoto (1991) identified a common TCR regulatory element by demonstrating binding of the enhancer-binding protein GATA3 to the enhancer elements of all 4 TCR genes
- GATA3 had been shown in the chicken to be an enhancer-binding protein containing a zinc finger domain
- GATA3 mRNA was demonstrated by Northern blot analysis in T cells but not in B cells or macrophages
- GATA3 is abundantly expressed in the T-lymphocyte lineage and is thought to participate in T-cell receptor gene activation through binding to enhancers
- Labastie et al
- (1994) cloned the human gene and the 5-prime end of the mouse gene
- The human gene comprises 6 exons distributed over 17 kb of DNA
- Its 2 zinc fingers are encoded by 2 separate exons highly conserved with those of GATA1, but no other structural homologies between the 2 genes could be found.