PIPA5105322

Phospho-Nkx2.1 (Ser23) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5105322-Each-of-1 In Stock ₹ 45,345.50

PIPA5105322 - Each of 1

₹ 45,345.50

In Stock

Quantity

1

Base Price: ₹ 45,345.50

GST (18%): ₹ 8,162.19

Total Price: ₹ 53,507.69

Antigen

Phospho-Nkx2.1 (Ser23)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

NKX2-1

Gene Alias

AV026640; BCH; BHC; homeobox protein NK-2 homolog A; Homeobox protein Nkx-2.1; NK-2; NK2 homeobox 1; NK-2 homolog A; NKX2.1; Nkx-2.1; NKX2-1; NKX2A; NMTC1; RNA polymerase I transcription termination factor; T/EBP; TEBP; Thyroid nuclear factor 1; thyroid transcription factor 1; thyroid transcription factor 1 TTF-1 NK-2; thyroid transcription factor 1-like; thyroid-specific enhancer-binding protein; tinman; TITF1; TTF1; TTF-1

Host Species

Rabbit

Purification Method

sequential chromatography

Regulatory Status

RUO

Gene ID (Entrez)

21869, 25628, 7080

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P23441, P43699, P50220

Gene Symbols

NKX2-1

Immunogen

A synthesized peptide derived from human NKX2-1(Accession P43699), corresponding to amino acid residues around phosphorylated Ser23.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of TTF1 only when phosphorylated at Ser23
  • This gene encodes a protein initially identified as a thyroid-specific transcription factor
  • The encoded protein binds to thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis
  • Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer
  • Multiple transcript variants encoding different isoforms have been found for this gene.