Phospho-MUSK (Tyr751) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5105381-Each-of-1 | In Stock | ₹ 46,680.50 |
PIPA5105381 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,680.50
GST (18%): ₹ 8,402.49
Total Price: ₹ 55,082.99
Antigen
Phospho-MUSK (Tyr751)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
MUSK
Gene Alias
CMS9; FADS; Mdk4; MGC126323; MGC126324; Mlk; muscle associated receptor tyrosine kinase; muscle localized kinase 2; muscle specific kinase (neural fold/somite kinase 1); muscle, skeletal receptor tyrosine protein kinase; Muscle, skeletal receptor tyrosine-protein kinase; muscle, skeletal, receptor tyrosine kinase; muscle-specific kinase receptor; muscle-specific protein kinase secretory isoform; muscle-specific tyrosine kinase receptor MuSK; muscle-specific tyrosine protein kinase receptor; Muscle-specific tyrosine-protein kinase receptor; MuSK; Nsk1; Nsk2; Nsk3; RP23-170A3.1
Host Species
Rabbit
Purification Method
sequential chromatography
Regulatory Status
RUO
Gene ID (Entrez)
18198, 4593, 81725
Content And Storage
-20°C
Form
Liquid
Applications
Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
O15146, Q61006, Q62838
Gene Symbols
MUSK
Immunogen
A synthesized peptide derived from human MUSK(Accession O15146), corresponding to amino acid residues around phosphorylated Tyr751.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of MuSK only when phosphorylated at Tyr751
- MUSK plays an important and selective role in many aspects of skeletal muscle development and function through the initial step of postsynaptic differentiation and formation of end-plate bands in cooperation with Rapsyn
- Communication between cells is often mediated by receptors on the surface of the target cell that are triggered by specific ligands released by other cells
- Receptor tyrosine kinase activity is strictly regulated by the binding of the appropriate ligand to the extracellular active site of the receptor
- MuSK has been shown to be part of the agrin signaling complex and plays an important role in the development and architectural maintenance of the neuromuscular junction.