PIPA5105456

Phospho-TrkA (Tyr791) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5105456-Each-of-1 In Stock ₹ 46,502.50

PIPA5105456 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

Phospho-TrkA (Tyr791)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Ntrk1

Gene Alias

C80751; DKFZp781I14186; EC 2.7.10.1; gp140trk; high affinity nerve growth factor receptor; kinase TrkA; MTC; neurotrophic receptor tyrosine kinase 1; Neurotrophic tyrosine kinase receptor type 1; neurotrophic tyrosine kinase, receptor, type 1; Ntrk1; Oncogene TRK; p140-TrkA; Slow nerve growth factor receptor; Tkr; TRK; TRK1; TRK1-transforming tyrosine kinase protein; Trka; Trk-A; TrkA neurotrophin receptor; trkA proto-oncogene receptor; tropomyosin-related kinase A; Tyrosine kinase receptor; Tyrosine kinase receptor A

Host Species

Rabbit

Purification Method

sequential chromatography

Regulatory Status

RUO

Gene ID (Entrez)

18211, 4914, 59109

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P04629, P35739, Q3UFB7

Gene Symbols

Ntrk1

Immunogen

A synthesized peptide derived from human NTRK1(Accession P04629), corresponding to amino acid residues around phosphorylated Tyr791.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of TrkA only when phosphorylated at Tyr791
  • NTRK1 (TRKA) belongs to the neurotrophic factor family of related polypeptides central to the development and maintenance of the mammalian nervous system
  • TrkA is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway
  • The presence of TrkA leads to cell differentiation and may play a role in specifying sensory neuron subtypes
  • Mutations in TrkA have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer.