PIPA5105133

Phospho-TrkA/TrkB (Tyr785, Tyr816) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5105133-Each-of-1 In Stock ₹ 44,099.50

PIPA5105133 - Each of 1

₹ 44,099.50

In Stock

Quantity

1

Base Price: ₹ 44,099.50

GST (18%): ₹ 7,937.91

Total Price: ₹ 52,037.41

Antigen

Phospho-TrkA/TrkB (Tyr785, Tyr816)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Ntrk2

Gene Alias

BDNF/NT-3 growth factors receptor; BDNF-tropomyosine receptor kinase B; C80751; gp140trk; GP145-TrkB; GP145-TrkB/GP95-TrkB; high affinity nerve growth factor receptor; MTC; neural receptor protein-tyrosine kinase (trkB); neurotrophic receptor tyrosine kinase 1; neurotrophic receptor tyrosine kinase 2; Neurotrophic tyrosine kinase receptor type 1; Neurotrophic tyrosine kinase receptor type 2; neurotrophic tyrosine kinase, receptor, type 1; neurotrophic tyrosine kinase, receptor, type 2; neurotrophic tyrosine receptor kinase type 2; NTRK1; NTRK2; Oncogene TRK; p140-TrkA; RATTRKB1; Slow nerve growth factor receptor; Tkr; Tkrb; trk; TRK1; TRK1-transforming tyrosine kinase protein; Trka; trk-A; TrkA neurotrophin receptor; trkA proto-oncogene receptor; TRKB; Trk-B; TrkB tyrosine kinase; TRKB1; Tropomyosin-related kinase A; tropomyosin-related kinase B; Tyrosine kinase receptor; Tyrosine kinase receptor A; tyrosine kinase receptor B

Host Species

Rabbit

Purification Method

sequential chromatography

Regulatory Status

RUO

Gene ID (Entrez)

18211, 18212, 25054, 4914, 4915, 59109

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P04629, P15209, P35739, Q16620, Q3UFB7, Q63604

Gene Symbols

NTRK1, Ntrk2

Immunogen

A synthesized peptide derived from human NTRK1(Accession P04629), corresponding to amino acid residues around phosphorylated Tyr785.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of TrkA /TrkB only when phosphorylated at Tyr785
  • This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family
  • This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway
  • The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes
  • Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer
  • Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date.