Phospho-eIF4E (Thr210) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5105472-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5105472 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
Phospho-eIF4E (Thr210)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Eif4e
Gene Alias
AUTS19; CBP; EG668879; EIF4E; EIF-4E; EIF4E1; EIF4EL1; Eif4e-ps; EIF4F; eIF-4F 25 kDa subunit; eukaryotic translation initiation factor 4E; eukaryotic translation initiation factor 4E-like 1; eukaryotic translation initiation factor 4E-like protein; eukaryotic translation initiation factor 4-like protein; If4e; MGC111573; mRNA cap-binding protein; OTTHUMP00000219703; OTTHUMP00000219704; OTTHUMP00000219705; translation initiation factor eIF-4E
Host Species
Rabbit
Purification Method
sequential chromatography
Regulatory Status
RUO
Gene ID (Entrez)
117045, 13684, 1977
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
P06730, P63073, P63074
Gene Symbols
Eif4e
Immunogen
A synthesized peptide derived from human EIF4E(Accession P06730), corresponding to amino acid residues around phosphorylated Thr210.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of eIF4E only when phosphorylated at Thr210
- eIF4E is involved in several cellular processes including enhanced translational efficiency, splicing, mRNA stability, and RNA nuclear export
- All eukaryotic cellular mRNAs are blocked at their 5-prime ends with the 7-methylguanosine cap structure, m7GpppX (where X is any nucleotide)
- EIF4E is a eukaryotic translation initiation factor involved in directing ribosomes to the cap structure of mRNAs
- It is a 24-kD polypeptide that exists as both a free form and as part of a multiprotein complex termed EIF4F
- The EIF4E polypeptide is the rate-limiting component of the eukaryotic translation apparatus and is involved in the mRNA-ribosome binding step of eukaryotic protein synthesis
- The other subunits of EIF4F are a 50-kD polypeptide, termed EIF4A, that possesses ATPase and RNA helicase activities, and a 220-kD polypeptide, EIF4G.