PIPA5105329

Phospho-eIF4A1 (Tyr48) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5105329-Each-of-1 In Stock ₹ 46,502.50

PIPA5105329 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

Phospho-eIF4A1 (Tyr48)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

EIF4A1

Gene Alias

ATP-dependent RNA helicase eIF4A-1; BM-010; DDX2A; Eif4; EIF4A; EIF-4A; Eif4a1; eIF-4A-I; eIF4A-I; eukaryotic initiation factor 4AI; Eukaryotic initiation factor 4A-I; eukaryotic translation initiation factor 4A, isoform 1; eukaryotic translation initiation factor 4A1; initiation factor eIF-4A long form; QtsA-12280; unnamed protein product

Host Species

Rabbit

Purification Method

sequential chromatography

Regulatory Status

RUO

Gene ID (Entrez)

13681, 1973, 287436

Content And Storage

-20°C

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P60842, P60843

Gene Symbols

EIF4A1

Immunogen

A synthesized peptide derived from human EIF4A1(Accession P60842), corresponding to amino acid residues around phosphorylated Tyr48.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of EIF4A1 only when phosphorylated at Tyr48
  • eIF4A2 is a 407 amino acid ATP-dependent RNA helicase belonging to the DEAD box helicase family
  • It contains one helicase ATP-binding domain and a helicase C-terminal domain
  • eIF4A2, a subunit of the eIF4F complex, acts as a protein-synthesis initiation factor and thus plays an important role in the binding of mRNA to the 43S pre-initiation complex of ribosomes
  • Human eIF4A2 interacts with the NS5B protein of Hepatitis C virus (HCV) and facilitates the genomic RNA synthesis of NS5B protein by unwinding the secondary structure of the HCV genome
  • It is ubiquitously expressed in most of normal tissues, but in variable amounts.