Cdc25A Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5109500-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5109500 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
Cdc25A
Classification
Polyclonal
Conjugate
Unconjugated
Gene
CDC25A
Gene Alias
CDC25 isoform A1-CAG; CDC25A; CDC25A2; CDC25A2-CAG isoform; Cdc25m3; cell division cycle 25A; D9Ertd393e; dual specificity phosphatase Cdc25A; EC 3.1.3.48; M-phase inducer phosphatase 1; MPIP1
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
12530, 171102, 993
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1.28 mg/mL
Formulation
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.
P30304, P48964, P48965
Gene Symbols
CDC25A
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 86-328 of CDC25A (NP_0017802)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: LDSPGPLDSK ENLENPMRRI HSLPQKLLGC SPALKRSHSD SLDHDIFQLI DPDENKENEA FEFKKPVRPV SRGCLHSHGL QEGKDLFTQR QNSAPARMLS SNERDSSEPG NFIPLFTPQS PVTATLSDED DGFVDLLDGE NLKNEEETPS CMASLWTAPL VMRTTNLDNR CKLFDSPSLC SSSTRSVLKR PERSQEESPP GSTKRRKSMS GASPKESTNP EKAHETLHQS LSLASSPKGT IEN CDC25a is a member of the CDC25 family of phosphatases
- Three CDC25 genes are present in human cells: CDC25A, CDC25B, and CDC25C
- These three genes function at different phases of the cell cycle
- CDC25a is required for progression through G1 and S phases of the cell cycle
- CDC25a activates the cyclin-dependent kinase CDC2 by removing two phosphate groups
- CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division
- CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated.