Phospho-Cdc25A (Ser178) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5104863-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5104863 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
Phospho-Cdc25A (Ser178)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
CDC25A
Gene Alias
CDC25 isoform A1-CAG; CDC25A; CDC25A2; CDC25A2-CAG isoform; Cdc25m3; cell division cycle 25A; D9Ertd393e; dual specificity phosphatase Cdc25A; EC 3.1.3.48; M-phase inducer phosphatase 1; MPIP1
Host Species
Rabbit
Purification Method
sequential chromatography
Regulatory Status
RUO
Gene ID (Entrez)
12530, 171102, 993
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
P30304, P48964, P48965
Gene Symbols
CDC25A
Immunogen
A synthesized peptide derived from human CDC25A(Accession P30304), corresponding to amino acid residues around phosphorylated Ser178.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of CDC25A only when phosphorylated at Serine 178
- CDC25a is a member of the CDC25 family of phosphatases
- Three CDC25 genes are present in human cells: CDC25A, CDC25B, and CDC25C
- These three genes function at different phases of the cell cycle
- CDC25a is required for progression through G1 and S phases of the cell cycle
- CDC25a activates the cyclin-dependent kinase CDC2 by removing two phosphate groups
- CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division
- CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated.