Phospho-Cdc25B (Ser353) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5104865-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5104865 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
Phospho-Cdc25B (Ser353)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
CDC25B
Gene Alias
AI604853; CDC25B; CDC25HU2; Cdc25m2; cell division cycle 25B; dual specificity phosphatase Cdc25B; EC 3.1.3.48; M-phase inducer phosphatase 2; MPIP2
Host Species
Rabbit
Purification Method
sequential chromatography
Regulatory Status
RUO
Gene ID (Entrez)
12531, 994
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
P30305, P30306
Gene Symbols
CDC25B
Immunogen
A synthesized peptide derived from human CDC25B(Accession P30305), corresponding to amino acid residues around phosphorylated Ser353.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Non-human Primate
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of CDC25B only when phosphorylated at Serine 353
- Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression
- Required for G2/M phases of the cell cycle progression and abscission during cytokinesis in a ECT2-dependent manner
- Directly dephosphorylates CDK1 and stimulates its kinase activity
- The three isoforms seem to have a different level of activity.