NEK3 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5110021-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5110021 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
NEK3
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Nek3
Gene Alias
glycogen synthase A kinase; HSPK 36; HSPK36; hydroxyalkyl-protein kinase; Nek3; Never in mitosis A-related kinase 3; NIMA (never in mitosis gene a)-related expressed kinase 3; NIMA (never in mitosis gene a)-related kinase 3; NIMA related kinase 3; NIMA-related expressed kinase 3; NIMA-related kinase 3; nimA-related protein kinase 3; phosphorylase B kinase kinase; serine/threonine-protein kinase Nek3
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
23954, 306576, 4752
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
1.52 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
P51956, Q9R0A5
Gene Symbols
Nek3
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 267-506 of human NEK3 (NP_689933.1).
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: PEIIMEYGEE VLEEIKNSKH NTPRKKTNPS RIRIALGNEA STVQEEEQDR KGSHTDLESI NENLVESALR RVNREEKGNK SVHLRKASSP NLHRRQWEKN VPNTALTALE NASILTSSLT AEDDRGGSVI KYSKNTTRKQ WLKETPDTLL NILKNADLSL AFQTYTIYRP GSEGFLKGPL SEETEASDSV DGGHDSVILD PERLEPGLDE EDTDFEEEDD NPDWVSELKK RAGWQGLCDR NIMA was originally shown in Aspergillus nidulans to be necessary for entry into mitosis
- NIMA-related mammalian proteins have since been identified as Nek1, Nek2, Nek3 and Nek4 (also designated STK2 or NRK2)
- High expression of Nek1 is seen in male and female germ cell lines of mouse
- Nek2 is the closest known mammalian relative to NIMA
- Like NIMA, Nek2 expression peaks at the G2 to M phase transition
- Nek3 is a predominantly cytoplasmic enzyme that was detectable in all organs studied
- Levels of Nek3 seem to remain unchanged throughout the cell cycle, but appear to be elevated in G0-arrested, quiescent fibroblasts
- In developing testicular germ cells, differential patterns of expression were seen for Nek1, Nek2 and Nek4, indicating possible overlapping, but non-identical functions.