PER2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5110098-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5110098 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
PER2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Per2
Gene Alias
circadian clock protein PERIOD 2; FASPS; FASPS1; hPER2; KIAA0347; mKIAA0347; mPer2; PER2; per2 {ECO:0000312; period 2; period circadian clock 2; period circadian protein 2; period circadian protein homolog 2; period circadian regulator 2; period homolog 2; RGD:61945}; rPER2
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
63840, 8864
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
0.73 mg/mL
Formulation
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.
O15055, Q9Z301
Gene Symbols
Per2
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 390-565 of human PER2 (NP_0737281)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: GQPFDYSPIR FRARNGEYIT LDTSWSSFIN PWSRKISFII GRHKVRVGPL NEDVFAAHPC TEEKALHPSI QELTEQIHRL LLQPVPHSGS SGYGSLGSNG SHEHLMSQTS SSDSNGHEDS RRRRAEICKN GNKTKNRSHY SHESGEQKKK SVTEMQTNPP AEKKAVPAME KDSLGV PER2, also known as Period circadian protein homolog 2, is a mainly nuclear protein that shows nucleocytoplasmic shuttling which is effected by interaction with other circadian core oscillator proteins and/or by phosphorylation
- PER2 belongs to the basic helix-loop-helix family of transcription factors and contains a PAC (PAS-associated C-terminal) domain and two PAS (PER-ARNT-SIM) domains
- PER2 is a component of the circadian core oscillator, which includes the CRY proteins, CLOCK or NPAS2, BMAL1 or BMAL2, CSNK1D and/or CSNK1E, TIMELESS, and the PER proteins
- This protein is thus essential for generating circadian rhythms and is a negative element in the circadian transcriptional loop which influences clock function by interacting with other circadian regulatory proteins and transporting them to the nucleus
- Expression of PER2 is fairly wide spread with strong expression in skeletal muscle and pancreas and slight expression in lung
- Defects in PER2 are a cause of familial advanced sleep-phase syndrome (FASPS).