Phospho-PER2 (Ser662) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5105052-Each-of-1 | In Stock | ₹ 45,345.50 |
PIPA5105052 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,345.50
GST (18%): ₹ 8,162.19
Total Price: ₹ 53,507.69
Antigen
Phospho-PER2 (Ser662)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Per2
Gene Alias
circadian clock protein PERIOD 2; FASPS; FASPS1; hPER2; KIAA0347; mKIAA0347; mPer2; PER2; per2 {ECO:0000312; period 2; period circadian clock 2; period circadian protein 2; period circadian protein homolog 2; period circadian regulator 2; period homolog 2; RGD:61945}; rPER2
Host Species
Rabbit
Purification Method
sequential chromatography
Regulatory Status
RUO
Gene ID (Entrez)
18627, 63840, 8864
Content And Storage
-20°C
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
O15055, O54943, Q9Z301
Gene Symbols
Per2
Immunogen
A synthesized peptide derived from human PER2(Accession O15055), corresponding to amino acid residues around phosphorylated Ser662.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of PER2 only when phosphorylated at Ser662
- PER2, also known as Period circadian protein homolog 2, is a mainly nuclear protein that shows nucleocytoplasmic shuttling which is effected by interaction with other circadian core oscillator proteins and/or by phosphorylation
- PER2 belongs to the basic helix-loop-helix family of transcription factors and contains a PAC (PAS-associated C-terminal) domain and two PAS (PER-ARNT-SIM) domains
- PER2 is a component of the circadian core oscillator, which includes the CRY proteins, CLOCK or NPAS2, BMAL1 or BMAL2, CSNK1D and/or CSNK1E, TIMELESS, and the PER proteins
- This protein is thus essential for generating circadian rhythms and is a negative element in the circadian transcriptional loop which influences clock function by interacting with other circadian regulatory proteins and transporting them to the nucleus
- Expression of PER2 is fairly wide spread with strong expression in skeletal muscle and pancreas and slight expression in lung
- Defects in PER2 are a cause of familial advanced sleep-phase syndrome (FASPS).