PGRMC2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5110103-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5110103 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
PGRMC2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Pgrmc2
Gene Alias
4631434O19Rik; 5730409G06Rik; DG6; Membrane-associated progesterone receptor component 2; Pgrmc2; PMBP; progesterone membrane binding protein; Progesterone membrane-binding protein; progesterone receptor membrane component 2; steroid receptor protein DG6
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
10424, 70804
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
1.89 mg/mL
Formulation
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.
O15173, Q80UU9
Gene Symbols
Pgrmc2
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1-50 of human PGRMC2 (NP_0063113)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: MAAGDGDVKL GTLGSGSESS NDGGSESPGD AGAAAEGGGW AAAALALLTG PGRMC2 (progesterone receptor membrane component 2), also known as DG6 (steroid receptor protein DG6) or PMBP (progesterone membrane-binding protein), is a single pass membrane protein belonging to the cytochrome b5 family (MAPR (membrane associated progesterone receptor) subfamily)
- Expressed in sperm, PGRMC2 is believed to function as a steroid receptor and may participate in the progesterone-dependent sperm acrosome reaction
- PGRMC2 shares approximately 50% overall sequence identity with its close relative PGRMC1
- The loss of the gene encoding PGRMC2 is associated with metastasis in uterine endocervical adenocarcinomas, implicating a potential role of PGRMC2 in the suppression of metastasis of endocervical adenocarcinomas.