ABCD4 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5110670-Each-of-1 | In Stock | ₹ 48,905.50 |
PIPA5110670 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,905.50
GST (18%): ₹ 8,802.99
Total Price: ₹ 57,708.49
Antigen
ABCD4
Classification
Polyclonal
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
O14678
Gene Symbols
ABCD4
Immunogen
Recombinant Protein corresonding to Human ABCD4
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Immunohistochemistry
Conjugate
Unconjugated
Gene
ABCD4
Gene Alias
69 kDa peroxisomal ABC-transporter; ABC41; ABCD4; ATP binding cassette subfamily D member 4; ATP-binding cassette sub-family D member 4; ATP-binding cassette, subfamily D (ALD), member 4; ATP-binding cassette, sub-family D (ALD), member 4; ATP-binding cassette, sub-family D, member 4; EST352188; MAHCJ; P69r; P70R; P79R; Peroxisomal membrane protein 1-like; Peroxisomal membrane protein 69; peroxisomal membrane protein, 70 kDa-related; PMP69; PMP70-related protein; Pxmp1l; PXMP1-L
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
5826
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Immunogen sequence: TLVSKNAFVC IYLISCFTQL IDLSTTLSDV AGYTHRIGQL RETLLDMSLK SQDCEILGES EWGLDTPPGW PAAEPADTAF LLERVSISAP SSDKPLIKDL SLKISEGQSL LITGNTGTGK The peroxisomal membrane contains several ATP-binding cassette (ABC) transporters, ABCD1-4 that are known to be present in the human peroxisome membrane
- All four proteins are ABC half-transporters, which dimerize to form an active transporter
- A mutation in the ABCD1 gene causes X-linked adreno-leukodystrophy (X-ALD), a peroxisomal disorder which affects lipid storage
- ABCD2 in mouse is expressed at high levels in the brain and adrenal organs, which are adversely affected in X-ALD
- The peroxisomal membrane comprises two quantitatively major proteins, PMP22 and ABCD3
- ABCD3 is associated with irregularly shaped vesicles which may be defective peroxisomes or peroxisome precursors
- ABCD1 localizes to peroxisomes
- ABCB7 is a half-transporter involved in the transport of heme from the mitochondria to the cytosol.