PIPA5111569

DUSP3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5111569-Each-of-1 In Stock ₹ 48,905.50

PIPA5111569 - Each of 1

₹ 48,905.50

In Stock

Quantity

1

Base Price: ₹ 48,905.50

GST (18%): ₹ 8,802.99

Total Price: ₹ 57,708.49

Antigen

DUSP3

Classification

Polyclonal

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

P51452

Gene Symbols

Dusp3

Immunogen

Recombinant Protein corresonding to Human DUSP3

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Immunocytochemistry

Conjugate

Unconjugated

Gene

Dusp3

Gene Alias

2210015O03Rik; 5031436O03Rik; dual specificity phosphatase 3; dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related); dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related)-like; dual specificity protein phosphatase 3; Dual specificity protein phosphatase VHR; DUSP 3; DUSP3; DUSP-3; RGD1560049; serine/threonine specific protein phosphatase; T-DSP11; Vaccinia H1-related phosphatase; vaccinia virus phosphatase VH1-related; VHR

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

1845

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Immunogen sequence: LVIAYLMMRQ KMDVKSALSI VRQNREIGPN DGFLAQLCQL NDRLAKEGKL KP Protein tyrosine phosphatases (PTPs) are a group of enzymes that remove phosphate groups from phosphorylated tyrosine residues on proteins
  • Together with tyrosine kinases, PTPs regulate the phosphorylation state of many important signaling molecules, such as the MAP kinase family
  • Recently, increasing attention has been focused on the growing family of PTPs
  • Like PTKs, PTPs have been implicated in cell signaling, cell growth and proliferation, and oncogenic transformation
  • Moreover, some PTPs can be involved in cell cycle regulation and embryogenesis
  • Dual specificity phosphatases (DSPs) are an emerging subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which appears to be selective for dephosphorylating the critical phosphothreonine and phosphotyrosine residues
  • The prototypical DSP is the VH1 gene in vaccinia virus expressed in late-stage viral infection
  • A shallow active site pocket in VHR allows for the hydrolysis of phosphorylated serine, threonine, or tyrosine protein residues, whereas the deeper active site of protein tyrosine phosphatases (PTPs) restricts substrate specificity to only phosphotyrosine.