Prolactin Receptor (ECD) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5112169-Each-of-1 | In Stock | ₹ 43,120.50 |
PIPA5112169 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,120.50
GST (18%): ₹ 7,761.69
Total Price: ₹ 50,882.19
Antigen
Prolactin Receptor (ECD)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
ECD
Gene Alias
5730461K03Rik; Ecd; ecdysoneless cell cycle regulator; ecdysoneless homolog; ecdysoneless homolog (Drosophila); GCR2; HSGT1; Human suppressor of GCR two; protein ecdysoneless homolog; protein SGT1; protein SGT1 homolog; SGT1; SGT1 protein; suppressor of GCR2; suppressor of S. cerevisiae gcr2
Host Species
Rabbit
Purification Method
Antigen affinity chromatography, Protein A
Regulatory Status
RUO
Gene ID (Entrez)
11319
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunoprecipitation, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.03% ProClin 300; pH 7
Gene Accession No.
O95905
Gene Symbols
ECD
Immunogen
E. coli-derived Human ECD fragment
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
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Description
- Regulator of p53/TP53 stability and function
- Inhibits MDM2-mediated degradation of p53/TP53 possibly by cooperating in part with TXNIP (PubMed:16849563, PubMed:23880345)
- May be involved transcriptional regulation
- In vitro has intrinsic transactivation activity enhanced by EP300
- May be a transcriptional activator required for the expression of glycolytic genes (PubMed:19919181, PubMed:9928932)
- Involved in regulation of cell cycle progression
- Proposed to disrupt Rb-E2F binding leading to transcriptional activation of E2F proteins (PubMed:19640839)
- The cell cycle -regulating function may depend on its RUVBL1-mediated association with the R2TP complex (PubMed:26711270)
- May play a role in regulation of pre-mRNA splicing (PubMed:24722212)
- [UniProt]