PIPA5114298

KCNE1L Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5114298-Each-of-1 In Stock ₹ 46,502.50

PIPA5114298 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

KCNE1L

Classification

Polyclonal

Conjugate

Unconjugated

Gene

KCNE5

Gene Alias

1500015C14Rik; AMME syndrome candidate gene 2 protein; AMMECR2; AMMECR2 protein; cardiac voltage-gated potassium channel accessory subunit 5; KCNE1L; KCNE1-like; Kcne5; Mink; MinK-like protein; potassium channel subunit beta MiRP4; potassium channel, voltage gated subfamily E regulatory beta subunit 5; potassium channel, voltage-gated Isk-related subfamily E regulatory beta subunit 5; potassium voltage-gated channel subfamily E member 1-like protein; Potassium voltage-gated channel subfamily E regulatory beta subunit 5; potassium voltage-gated channel subfamily E regulatory subunit 5; potassium voltage-gated channel, Isk-related family, member 1-like; potassium voltage-gated channel, Isk-related family, member 1-like, pseudogene; voltage-gated potassium channel accessory subunit 5

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

23630

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

0.5 mg/mL

Formulation

PBS with 2% sucrose and 0.09% sodium azide

Gene Accession No.

Q9UJ90

Gene Symbols

KCNE5

Immunogen

Synthetic peptide directed towards the N terminal region of human KCNE1L

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: RLRTLLSRLL LELHHRGNAS GLGAGPRPSM GMGVVPDPFV GREVTSAKGD For short term use, store at 2-8°C up to 1 week
  • For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles
  • Kcne1 is a member of Voltage-gated potassium (Kv) channels that represent the most complex class of voltage-gated ion channels from both functional and structural standpoints
  • The diverse functions of Kv channels include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume
  • The Kcne1 gene encodes a membrane protein which has sequence similarity to the KCNE1 gene product, a member of the potassium channel, voltage-gated, isk-related subfamily
  • Kcne1, an intronless gene is deleted in AMME contiguous gene syndrome and may be involved in the cardiac and neurologic abnormalities found in the AMME contiguous gene syndrome
  • Functionally, Kcne1 is a potassium channel ancillary subunit that is essential for generation of some native K(+) currents by virtue of formation of heteromeric ion channel complex with voltage-gated potassium (Kv) channel pore-forming alpha subunits
  • Kcne1 also functions as an inhibitory beta-subunit of the repolarizing cardiac potassium ion channel KCNQ1
  • Diseases associated with KCNE1 include Jervell And Lange-Nielsen Syndrome 2 and Long Qt Syndrome 5.