KCNK18 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5114308-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5114308 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
KCNK18
Classification
Polyclonal
Conjugate
Unconjugated
Gene
KCNK18
Gene Alias
2P K ion channel TRESK; Gm781; K2p18.1; Kcnk18; MGR13; Potassium channel subfamily K member 18; potassium channel, subfamily K, member 18; potassium channel, two pore domain subfamily K, member 18; potassium two pore domain channel subfamily K member 18; tandem-pore K+ (K(2P)) channel; Tresk; TRESK2; Tresk-2; TRIK; TWIK-related individual K+ channel; TWIK-related individual potassium channel; TWIK-related spinal cord K+ channel; TWIK-related spinal cord potassium channel; Two-pore-domain potassium channel TRESK
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
332396, 338567, 445371
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.
Q6Q1P3, Q6VV64, Q7Z418
Gene Symbols
KCNK18
Immunogen
Synthetic peptide within mouse KCNK18 aa 44-93
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- TRESK (TWIK-related spinal cord K+ channel) is a two-pore domain K+ channel that induces outward rectification and functions as a background K+ channel that is abundantly expressed in the spinal cord, thymus, spleen, and leukemic T-lymphocytes
- TRESK is activated by increased cytoplasmic calcium concentration through calcineurin as well as by acetylcholine and histamine
- It has been suggested that TRESK is linked to acute and chronic pain by activation of calcineurin
- Other studies indicate that TRESK may play a role in the regulation of T-cell function and could be an excellent target to treat T-cell originated immune dysfunction.