PIPA5114756

KCNN1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5114756-Each-of-1 In Stock ₹ 46,502.50

PIPA5114756 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

KCNN1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Kcnn1

Gene Alias

AI854248; hSK1; KCa2.1; Kcnn1; potassium calcium-activated channel subfamily N member 1; potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1; potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1; potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1-like; SK; Sk1; SKCa 1; SKCa1; small conductance Ca2+-activated K+ channel type1; small conductance calcium-activated potassium channel 1; small conductance calcium-activated potassium channel protein 1

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3780, 54261, 84036

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.

P70606, Q92952, Q9EQR3

Gene Symbols

Kcnn1

Immunogen

A synthesized peptide derived from human KCNN1(Accession Q92952), corresponding to amino acid residues R390-V440.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total KCNN1
  • Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron
  • Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels
  • The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP
  • The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits
  • KCNN1 is a member of the KCNN family of potassium channels.